Continuous Fluorescence Assays for Reactions Involving Adenine
نویسندگان
چکیده
منابع مشابه
Chelation reactions of adenine.
Chelation reactions of the antimitotic drug, 6-amino-purine (adenine; abbr. ADN) with the metal ions: Be ( I I ) , AI ( I II ) , Cr ( I I I ) , M n ( I I ) , Fe ( I I I ) , Co (II ) , N i ( I I ) , C u ( I I ) , P b ( I I ) , and U 0 2 ( I I ) have been investigated in aqueous solution at 3 0 ° using B j e r r u m C a l v i n pH titration technique. The formation constants have been determined ...
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Indoleamine 2,3-dioxygenase (IDO1) and tryptophan 2,3-dioxygenase (TDO) are two structurally different enzymes that have a different tissue distribution and physiological roles, but both catalyze the conversion of tryptophan to N-formylkynurenine (NFK). IDO1 has been clinically validated as a small-molecule drug target for cancer, while preclinical studies indicate that TDO may be a target for ...
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A series of pentacyclic heterocyclic systems (15 examples, 69-89%) have been synthesized using intramolecular Povarov reactions involving 3-aminocoumarins and O-cinnamylsalicylaldehydes. The Povarov adducts are formed with high selectivity for the trans,trans relative stereochemistry in the newly-formed [6,6] fused ring system. One example of a Povarov adduct featuring a new [6,5] fused ring sy...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2016
ISSN: 0003-2700,1520-6882
DOI: 10.1021/acs.analchem.6b03621